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An Introduction to Human Molecular Genetics: Mechanisms of Inherited Diseases, 2nd Edition
Jack J. Pasternak,
Univ. of Waterloo, Ontario, Canada
ISBN: 978-0-471-47426-5
©2005
656 pages
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Description
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This revision provides the most coverage of the molecular genetics of human inherited diseases, explaining the interaction of genes and their products, and the consequences of these mechanisms on disease states in major organ systems. It includes essential basic biology of each system for a broader context for the study of disease than that found in other texts. In this edition, functional genomics, proteomics, and microarray technology are covered in much more detail, with new chapters on human population genetics, complex human disease, human genetic diversity, and genomic imprinting for enhanced utility in undergraduate biology courses. In addition, the section on human gene therapy has been completely rewritten and expanded to cover clinical genetics broadly, from diagnostic testing to molecular screening, and treatment.
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